Michelle Visage auditioned for and won a place in Seduction, an R&B and dance vocal trio assembled by Robert Clivilles and David Cole and that signed with A&M Records in 1990. The group had several pop and dance hits, including "Two to Make It Right". After the group's breakup, Visage collaborated with freestyle dance act TKA as a guest vocalist on the song "Crash (Have Some Fun)".
In 1992, she provided lead vocals to another dance act assembled by Clivilles & Cole, The S.O.U.L. S.Y.S.T.E.M. Its song "It's Gonna Be a Lovely Day", a cover version of the Bill Withers song "Lovely Day", was included on the soundtrack to The Bodyguard and became a #1 dance single that year, peaking at #34 on the Billboard Hot 100 early the next year.
In 1996 Visage became the co-host of RuPaul's VH1 talk show The RuPaul Show. She also co-hosted RuPaul on WKTU's morning show from 1996-2002. She has also hosted such television programming as VH1's red carpet coverage of the 1998 Grammys and, in 2002, Grease's 25th-anniversary re-release party.
Visage was co-host of The Jamz Session on Hot 92 Jamz (KHHT) in Los Angeles from 2002-2005. In 2005, she returned to New York City where she served as co-host of The Morning Mix on (WNEW-FM) until December 2006. During the later part of 2006 she was also heard on Sirius Satellite Radio's The Beat 36, but left Sirius. On March 12, 2007, she became a co-host of the morning show on SUNNY 104.3 in West Palm Beach, Florida. On January 10, 2011, she joined 93.9 MIA in Miamias the host of the new MIA Morning Show on 93.9 MIA in Miami; she left Miami and WMIA in December 2011 and moved back to Los Angeles. On January 24, 2011, Visage debuted as the second permanent judge on the Logo TV's reality-television series RuPaul's Drag Race, where she replaced former judge Merle Ginsberg, after assassinating her with her tits. She was also on Celebrity Big Brother 15 and came 4th.
- "Bitch, you're here!"
- "Stop relying on that body!"
"I push up my boobs for Jesus."
"My tits so high, they choking me."
- "I hate the Oprah Winfrey Network."
- "Square up, cunty." to Jinkx Monsoon
- "Did you forget who you are? You're a boy wearin' a dress, bitch!" (From Johnny McGovern's "Hey Qween!")